全文获取类型
收费全文 | 144篇 |
免费 | 1篇 |
出版年
2014年 | 2篇 |
2013年 | 6篇 |
2012年 | 3篇 |
2011年 | 8篇 |
2010年 | 8篇 |
2009年 | 15篇 |
2008年 | 6篇 |
2007年 | 6篇 |
2006年 | 9篇 |
2005年 | 4篇 |
2003年 | 1篇 |
2002年 | 3篇 |
2001年 | 1篇 |
1998年 | 1篇 |
1997年 | 3篇 |
1996年 | 4篇 |
1995年 | 5篇 |
1994年 | 3篇 |
1993年 | 2篇 |
1992年 | 2篇 |
1991年 | 3篇 |
1990年 | 3篇 |
1989年 | 2篇 |
1988年 | 1篇 |
1985年 | 1篇 |
1984年 | 3篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1980年 | 2篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1975年 | 2篇 |
1974年 | 1篇 |
1973年 | 4篇 |
1972年 | 3篇 |
1971年 | 5篇 |
1968年 | 1篇 |
1967年 | 1篇 |
1965年 | 1篇 |
1963年 | 1篇 |
1961年 | 1篇 |
1959年 | 1篇 |
1956年 | 1篇 |
1954年 | 1篇 |
1953年 | 1篇 |
1935年 | 1篇 |
1934年 | 3篇 |
1933年 | 1篇 |
1931年 | 1篇 |
1919年 | 1篇 |
排序方式: 共有145条查询结果,搜索用时 15 毫秒
101.
SYNOPSIS. In this review we describe data of experiments whichinterfere with the formation of the metameric pattern duringembryogenesis. Ligating embryos before blastoderm stage leadsto a gap in the segmentation pattern of the differentiated embryo.The gap can extend up to 6 segments but terminal segments arealways recognizable. In posterior but not in anterior fragmentswe find abnormally large but fewer segments. This increase insegment size results from a different determination of blastodermcells after ligation. During nuclear multiplication stages whena gap can be produced, the zygotic genome is not yet active.Information to develop the metameric pattern in ligated embryosmust therefore have been made during oogenesis. Recently Nüisslein-Volhard and Wieschaus (1980) have describedthree zygotic mutations which form embryos with a gap of segmentssimilar to our ligated embryos. We have discussed these mutantphenotypes in connection with our experimental data. Segmentation is controlled at several levels. During oogenesisthe anterior-posterior and dorsal-ventral axes become established(Nüsslein-Volhard, 1979). Also during oogenesis, but extendinginto early embryonic life, information is generated to subdividethe embryo into blocks of cells forming the metameric pattern.At blastoderm the identity of segments becomes established. 相似文献
102.
KIYOSHI SANO TAKEO KISHIMOTO SUMI L. KOIDE HARUO KANATANI SAMUEL S. KOIDE 《Development, growth & differentiation》1979,21(5):457-464
Nicotinamide inhibited both germinal vesicle breakdown (GVBD) and polar body formation (PBF) in surf clam and starfish oocytes. In the surf clam nicotinamide at 0.3 mM completely blocked PBF in the fertilized oocytes. For blockage of GVBD higher concentration was required. In the starfish, nicotinamide (30 mM) prevented PBF but not GVBD, when added 7 min after the commencement of 1-methyladenine (1-MeAde) administration. These results suggest that PBF is blocked by nicotinamide independent of its effect on GVBD. In the case of starfish, NAD+was more effective than nicotinamide in inhibiting oocyte maturation. Nicotinamide also blocked GVBD induced by microinjection of the cytoplasm containing maturation-promoting factor (MPF) obtained from 1-MeAde-treatcd oocytes. These results suggest that nicotinamide prevents the action of MPF rather than inhibiting the interaction of 1-McAde with cell membrane or the induction of MPF. 相似文献
103.
104.
105.
STEPHANE STENUITE SAMUEL PIRLOT ANNE-LAURE TARBE HUGO SARMENTO MÉLANIE LECOMTE SOPHIE THILL BRUNO LEPORCQ DANNY SINYINZA JEAN-PIERRE DESCY PIERRE SERVAIS 《Freshwater Biology》2009,54(6):1300-1311
1. Abundance and bacterial production (BP) of heterotrophic bacteria (HBact) were measured in the north and south basins of Lake Tanganyika, East Africa, during seasonal sampling series between 2002 and 2007. The major objective of the study was to assess whether BP can supplement phytoplankton particulate primary production (particulate PP) in the pelagic waters, and whether BP and particulate PP are related in this large lake. HBact were enumerated in the 0–100 m surface layer by epifluorescence microscopy and flow cytometry; BP was quantified using 3H‐thymidine incorporation, usually in three mixolimnion layers (0–40, 40–60 and 60–100 m). 2. Flow cytometry allowed three subpopulations to be distinguished: low nucleic acid content bacteria (LNA), high nucleic acid content bacteria (HNA) and Synechococcus‐like picocyanobacteria (PCya). The proportion of HNA was on average 67% of total bacterial abundance, and tended to increase with depth. HBact abundance was between 1.2 × 105 and 4.8 × 106 cells mL−1, and was maximal in the 0–40 m layer (i.e. roughly, the euphotic layer). Using a single conversion factor of 15 fg C cell−1, estimated from biovolume measurements, average HBact biomass (integrated over a 100‐m water column depth) was 1.89 ± 1.05 g C m−2. 3. Significant differences in BP appeared between seasons, especially in the south basin. The range of BP integrated over the 0–100 m layer was 93–735 mg C m−2 day−1, and overlapped with the range of particulate PP (150–1687 mg C m−2 day−1) measured in the same period of time at the same sites. 4. Depth‐integrated BP was significantly correlated to particulate PP and chlorophyll‐a, and BP in the euphotic layer was on average 25% of PP. 5. These results suggest that HBact contribute substantially to the particulate organic carbon available to consumers in Lake Tanganyika, and that BP may be sustained by phytoplankton‐derived organic carbon in the pelagic waters. 相似文献
106.
MICHAEL NOTARO YI WANG ZHENGYU LIU ROBERT GALLIMORE SAMUEL LEVIS 《Global Change Biology》2008,14(2):347-368
A negative feedback of vegetation cover on subsequent annual precipitation is simulated for the mid‐Holocene over North Africa using a fully coupled general circulation model with dynamic vegetation, FOAM‐LPJ (Fast Ocean Atmosphere Model‐Lund Potsdam Jena Model). By computing a vegetation feedback parameter based on lagged auto‐covariances, the simulated impact of North African vegetation on precipitation is statistically quantified. The feedback is also dynamically assessed through initial value ensemble experiments, in which North African grass cover is initially reduced and the climatic response analyzed. The statistical and dynamical assessments of the negative vegetation feedback agree in sign and relative magnitude for FOAM‐LPJ. The negative feedback on annual precipitation largely results from a competition between bare soil evaporation and plant transpiration, with increases in the former outweighing reductions in the latter given reduced grass cover. This negative feedback weakens and eventually reverses sign over time during a transient simulation from the mid‐Holocene to present. A similar, but weaker, negative feedback is identified in Community Climate System Model Version 2 (CCSM2) over North Africa for the mid‐Holocene. 相似文献
107.
JEANINE C. BOND SAMUEL A. IVERSON N. BETH MACCALLUM CYNDI M. SMITH HOWARD J. BRUNER DANIEL ESLER 《The Journal of wildlife management》2009,73(6):965-972
ABSTRACT Quantifying sources of variation in demographic rates can provide insight into processes underlying population dynamics and subsequently direct wildlife conservation. In the context of avian life history, understanding patterns of variation in survival rates of breeding females is particularly relevant because this cohort often has a disproportionately large effect on population dynamics. We estimated survival probability for 144 adult female harlequin ducks (Histrionicus histrionicus) that we marked with radiotransmitters and tracked at 4 breeding areas in western North America. Model selection results indicated both regional and temporal variation in survival rates, with most mortality attributed to predation. Cumulative survival probability (±SE) during the 100-day study period was lower at 2 sites in the Rocky Mountains of Alberta, Canada (AB1 and AB2: 0.75 ± 0.11) than in the Coast Mountains of British Columbia, Canada (BC: 0.88 ± 0.08) or the Cascade Mountains of Oregon, USA (OR: 0.89 ± 0.08). Survival also was lower during incubation than nest-initiation or brood-rearing stages at all 4 study areas. In comparison to other annual cycle stages and locations, harlequin duck mortality rates were highest on the breeding grounds, suggesting that management actions designed to reduce mortality during breeding would achieve meaningful population-level benefits. 相似文献
108.
109.
VIRGINIA Laifun Lee MARIA Lauching Young TONY Kingtung Chan SAMUEL Kinsan Lam FRANCO Kwokyan Ng JULIA Wingyin Chan 《水生生物学报》2006,12(6):1-666
Hong Kong Special Administrative Region,China,has an area of1095km2and is located at the edge of thenorthern tropical zone.The landscape is dominated byhills and ravines withflat landrestrictedtothe lowflood-plains and coastal regions.Inthis hilly domain,the smallrocky streams are typically fast flowing at their uplandsources,and graduallyreduceinspeed asthey wind alonghill cuttings to reach the lowlands.While streams arecommonlyfound,rivers are very limited in number.Thefewlong and meanderi… 相似文献
110.
TOVA ZINMAN SAMUEL SALZBERG ZVI MALIK ASHER SHAINBERG 《Cell biology international》1997,21(3):133-144
The present work is an attempt to explain the high resistance of muscles to cancer development. We used primary cultures of rat skeletal and cardiac muscle, and examined the effect of the supernatant of these cultures (conditioned medium; CM) on proliferation of cancer cells. The results demonstrated that CM inhibited the proliferation of several types of malignant cells by more than 50%, without a significant inhibition on normal cells. Cell cycle analysis revealed that CM increased the number of cells in S and G2 phases, suggesting a cytostatic effect of CM. For defining the biological properties of the factor(s) which are present in the CM, skeletal muscle cultures were grown in chemically defined medium (serum free medium). The concentrated sample was applied to a Sephadex G-50 column and three fractions were obtained. Only one fraction showed inhibitory activity. Four protein bands were observed in this fraction, as revealed by SDS-PAGE. We suggest that some, or all of these proteins are responsible for inhibition of tumor cell replication. 相似文献